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Ashwagandha

Withania somnifera

Ashwagandha
Wikimedia Commons · Wowbobwow12 · Image source · CC BY-SA 3.0

Overview

Arthritis. Anxiety. Insomnia. Chronic liver disease. Tuberculosis. Tumors. Oral use also listed: aphrodisiac, emmenagogue, decreasing inflammation, emaciation, fibromyalgia, hiccups, immunomodulatory effects, improving cognitive function, infertility (men and women), menstrual disorders, preventing effects of aging (per text). Topical use: backache, hemiplegia, ulcerations (per text).

Plant family

Solanaceae

Parts used

Root, berries, and leaves

Actions

Adaptogen · Nervine · Tonic

Affinities

Nervous · Immune · Reproductive

Body systems

Nervous · Immune · Reproductive

Taste profile

Bitter

Tissue states

Cold · Dry · Atrophy

Traditional use

Ayurvedic rasayana-style tonic for vitality, strength, and convalescence/depletion patterns; used for tumors, inflammation, arthritis, asthma, hypertension, and elderly cognitive concerns in traditional framings (per text).

Current use

Arthritis. Anxiety. Insomnia. Chronic liver disease. Tuberculosis. Tumors. Oral use also listed: aphrodisiac, emmenagogue, decreasing inflammation, emaciation, fibromyalgia, hiccups, immunomodulatory effects, improving cognitive function, infertility (men and women), menstrual disorders, preventing effects of aging (per text). Topical use: backache, hemiplegia, ulcerations (per text).

Preparation

Powder; tonic; extract; decoction; poultice

Dosage guidance

Powder: 1–6 g daily in capsule, or up to 5–10 g as an occasional tonic. Tonic: 1/2–3/4 t (2–4 mL) 3× daily. Extract: 2 T up to 3× daily. Decoction: boil 3/4–1 1/4 t (3–6 g) root in water for 15 min; drink 3 cups/day. Poultice: topical use for sore joints.

Cautions & contraindications

May affect thyroid function tests (TSH/T3/T4) and may stimulate thyroid synthesis/secretion. Contraindicated with sedatives or anxiolytics (possible potentiation). Contraindicated for people with stomach ulcers (possible GI irritant effect). Do not use during pregnancy (anecdotal abortifacient concern when used orally). Use cautiously with hypotension or antihypertensives, peptic ulcers, sedative drugs, and thyroid disorders (per text). AHPA Class 2b (not to be used during pregnancy).

Evidence notes

Course text summarizes wide-ranging preclinical findings (e.g., NFkappaB inhibition, antimicrobial activity, apoptosis/cancer cell line effects) and includes clinical trial notes for anemia and arthritis; translate to practice cautiously and screen for contraindications.